For most people, the Covid vaccine does not cause adverse health effects – but a small percentage experience chronic symptoms that can last for months or even years.
Yale researchers have recently made some discoveries about why some people experience this condition, which they called “post-vaccine syndrome” (PVS).
In early findings, the team recognized “possible immunological patterns”, which are unique to people with PVS. The hope is that this discovery will help enable future treatments and therapies for those affected.
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“This work is still in its early stages, and we must validate these findings,” said the author of the study study Akiko Iwasaki, a sterling professor of immunobiology at Yale School of Medicine, in a press release.
Yale researchers have recently made some discoveries about why some people experience “post-vaccine syndrome” (PVS). (istock)
“But this gives us some hope that there may be something we can use for diagnosis and treatment of PVs in the way.”
Symptoms of post-vaccine syndrome
People with this condition may suffer excessive fatigue, exercise intolerance, brain mist, insomnia and dizziness, according to Yale researchers.
These usually develop within a day or two of vaccination and can get worse over time.
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“It is clear that some individuals experience important challenges after vaccination. Our responsibility as scientists and clinicians is to listen to their experiences, rigorously explore the underlying causes and seek ways to help,” said companion Harlan Krumholz, professor of cardiology at YSM, in the edition.
“Post-vaccinating syndrome is real, and has been found (occurring) from many vaccines, including Covid,” Dr. Marc Siegel, clinical professor of medicine at NYU Langone Health and Fox News Senior Medical Analyst, told Fox News Digital.
What did the study find
The researchers analyzed blood samples from 42 study participants who experienced symptoms of PVS and 22 that did not.
Those with symptoms have been shown that they have lower levels of two types of white blood cells. People with PVs, who never had Covid, also had lower levels of antibodies against the SARS-Cov-2 Spike protein, probably because they tended to have fewer vaccine doses, according to the release.
“Post-vaccinating syndrome is real, and has been found (occurring) from many vaccines.”
“Fewer vaccine doses and no viral infection means that the body’s immune system had little opportunity to develop defense to the virus,” the researchers said.
Some of the people with PVS also had higher levels of the SARS-Cov-2 Spike protein, which allows the virus to penetrate and infect host cells. This has also been attached to a higher risk of developing a long cover.
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“We do not know if the level of spicy protein causes chronic symptoms, as there were other participants with PVs who had no measurable spicy protein – but it could be one mechanism under that syndrome,” said Iwasaki.
People with the syndrome can suffer excessive fatigue, exercise intolerance, brain mist, insomnia and dizziness, according to Yale’s researchers. (istock)
In addition to the raised spice proteins, other factors could increase the risk of post-vaccination syndrome. These include autoimmunity, histical damage and reactivation of Epstein-Barr virus (EBV), the researchers wrote.
“Akiko Iwasaka is a world-famous immunologist at Yale, who studied extensively Covid (and Covid vaccines),” Siegel pointed out.
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“In this new study, she reports that in a very small percentage of those who received Covid vaccines (and experienced extended side effects), there may be the presence of a constant spike -protein,” Siegel confirmed.
“They can also experience immune interruption, which takes the form of heights in inflammatory immune cells (CD8 and TN alpha) and decrease of cells that help resolve inflammation and infection (CD4 help cells).”
“Every medical intervention risks some risk, and it is important to acknowledge that adverse events can occur with vaccines.” (Reuters/Dado Ruvic/Illustration/File Photo)
The researchers agreed that more studies are essential to guide diagnosis and treatment.
“We’re just starting to go ahead to understand PVS,” said Krumholz. “Every medical intervention risks some risk, and it is important to acknowledge that adverse events can occur with vaccines.”
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“Our focus should remain to understand what these people experience through rigorous science and deal with the needs of those affected by mercy and open mind.”
Siegel agreed, adding, “This must be further studied to understand how common extended side effects of Covid vaccine and how to predict them and treat them.”
