Obesity and stress could increase the risk of one of the most aggressive types of cancer, a new study suggests.
Researchers at the University of California Los Angeles (UCLA) have found that stress-related neurotransmitters and obesity hormones activated CREB (Cyclic AMP response element-binding protein), which has been shown to promote the growth of cancer cells in the pancreas.
In the study, mice that ate a high fat diet more likely developed pre -cancer injuries. When stress levels were also raised by social isolation, the lesions grew even more.
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The risk of cancer related to stretching was more pronounced in female mice.
Based on these findings, the researchers have suggested investigating the use of existing drugs to reduce the risk of obesity and tight cancers.
Obesity and stress could increase the risk of one of the most aggressive types of cancer, a new study suggests. (istock)
“Because β-adrenergic receptors play an important role in growth of cancer relationships, often used beta blockers, which are drugs prescribed for high blood pressure, could be repulsed to help mitigate these effects,” a press release stated.
Pancreatic cancer is one of the deadliest types in the United States, with a five -year survival percentage of only 13%.
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One of the biggest challenges with the disease is that it is often detected in a late stage, when the disease is already progressing, according to Dr. Robert Den, radio oncologist, professor of radio oncology and general practitioner at Alpha Tau Medical in Israel.
“Unlike some other cancers, there are no effective early sick tools, so when a patient is diagnosed, medical options are often limited,” Den, which was not involved in the study, told Fox News Digital.
“Unlike some other cancers, there are no effective early sick tools, so when a patient is diagnosed, treatment options are often limited.” (istock)
The study strengthens the strong relationship between the mind and body, as it related to cancer development, Den said.
“Stress and its associated paths can exacerbate the progress of disease, and we know that obesity fosters certain cancers, possibly affecting a patient’s response to treatment,” he said.
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“In this case, we see evidence that stress and obesity can contribute to worsening pancreatic cancer, which has major implications for both preventive and medical strategies.”
Maintaining a heart-health diet and eating moderately is essential, Den noted-not only for cancer prevention but for overall health.
Pancreatic cancer is one of the deadliest types in the United States, with a five -year survival percentage of only 13%. (istock)
“Exercise is particularly crucial to dealing with both obesity and stress,” he said. “Stay active is not only useful for physical health, but also a great way to reduce stress.”
Mindfulness can also play a key role in reducing cancer risk, the doctor advised.
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“Spending time outdoors can also improve both mental and physical well -being, so I always encourage patients to find ways to be active, connect with nature and prioritize their overall well -being,” he said.
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As for pancreatic cancer, treatment, Den realized that there were some advances in chemotherapy and surgical techniques, but “there was still no advance.”
“Most immune therapies, which were revolutionary in other cancers, did not show the same promise in pancreatic cancer,” he said.
“Spending time outdoors can also improve both mental and physical well -being, so I always encourage patients to find ways to be active, connect with nature and prioritize their overall well -being,” oncologist said. (istock)
“The core challenge is to find ways to help patients who are not candidates for surgery, as surgery remains the best defense.”
Fox News Digital reached the study researchers for comment.
