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    Scientists uncover a crucial component for restoring functional activity after spinal cord injury

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    Improving treatment outcomes for individuals with acute spinal cord injury

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    Multipronged gene therapy restores walking in mice after complete spinal cord injury

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    NIH grants support Kessler Foundation scientists to advance research on neglect dyslexia and autism

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    Processing speed influences memory rehabilitation outcomes in TBI patients

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    Two more universities set to join IUCRC BRAIN at University of Houston to advance neurotechnology

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    New online course helps personal care assistants better understand spinal cord injury

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    New review looks at the impact of robotic exoskeletons on recovery of ambulation among individuals with acquired brain injury

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    Kessler Foundation researchers receive $1.7 million in grants to improve lives of TBI patients

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    Progress for paralyzed patients: First implanted device is placed to restore arm, hand and finger movement

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    For autoimmune disease sufferers, ginger may ‘play a critical role’ in controlling inflammation, study finds

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    As amoxicillin shortage continues, prescriptions have plummeted, study finds: ‘Immediate, sweeping effect’

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    Bruce Willis’ FTD battle: Expert shares warning signs and what to know about the condition

    Depression risk spikes for those who eat these unhealthy foods, study finds: ‘Not a coincidence’

    Depression risk spikes for those who eat these unhealthy foods, study finds: ‘Not a coincidence’

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    Dengue fever: What you need to know about the mosquito-borne illness sweeping Jamaica

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    Less than half of nurses are ‘fully engaged’ at work, while many are ‘unengaged,’ new report reveals

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    Jellyfish are not the ‘simple creatures’ once thought: New study may change an understanding of our own brains

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    Aspartame and autism: Drinking diet soda amid pregnancy linked to diagnosis in male offspring, says study

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    Scientists uncover a crucial component for restoring functional activity after spinal cord injury

    Scientists uncover a crucial component for restoring functional activity after spinal cord injury

    Improving treatment outcomes for individuals with acute spinal cord injury

    Improving treatment outcomes for individuals with acute spinal cord injury

    Multipronged gene therapy restores walking in mice after complete spinal cord injury

    Multipronged gene therapy restores walking in mice after complete spinal cord injury

    NIH grants support Kessler Foundation scientists to advance research on neglect dyslexia and autism

    NIH grants support Kessler Foundation scientists to advance research on neglect dyslexia and autism

    Processing speed influences memory rehabilitation outcomes in TBI patients

    Processing speed influences memory rehabilitation outcomes in TBI patients

    Two more universities set to join IUCRC BRAIN at University of Houston to advance neurotechnology

    Two more universities set to join IUCRC BRAIN at University of Houston to advance neurotechnology

    New online course helps personal care assistants better understand spinal cord injury

    New online course helps personal care assistants better understand spinal cord injury

    New review looks at the impact of robotic exoskeletons on recovery of ambulation among individuals with acquired brain injury

    New review looks at the impact of robotic exoskeletons on recovery of ambulation among individuals with acquired brain injury

    Kessler Foundation researchers receive $1.7 million in grants to improve lives of TBI patients

    Kessler Foundation researchers receive $1.7 million in grants to improve lives of TBI patients

  • Spine
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    Progress for paralyzed patients: First implanted device is placed to restore arm, hand and finger movement

    Progress for paralyzed patients: First implanted device is placed to restore arm, hand and finger movement

    For autoimmune disease sufferers, ginger may ‘play a critical role’ in controlling inflammation, study finds

    For autoimmune disease sufferers, ginger may ‘play a critical role’ in controlling inflammation, study finds

    As amoxicillin shortage continues, prescriptions have plummeted, study finds: ‘Immediate, sweeping effect’

    As amoxicillin shortage continues, prescriptions have plummeted, study finds: ‘Immediate, sweeping effect’

    Bruce Willis’ FTD battle: Expert shares warning signs and what to know about the condition

    Bruce Willis’ FTD battle: Expert shares warning signs and what to know about the condition

    Depression risk spikes for those who eat these unhealthy foods, study finds: ‘Not a coincidence’

    Depression risk spikes for those who eat these unhealthy foods, study finds: ‘Not a coincidence’

    Dengue fever: What you need to know about the mosquito-borne illness sweeping Jamaica

    Dengue fever: What you need to know about the mosquito-borne illness sweeping Jamaica

    Less than half of nurses are ‘fully engaged’ at work, while many are ‘unengaged,’ new report reveals

    Less than half of nurses are ‘fully engaged’ at work, while many are ‘unengaged,’ new report reveals

    Jellyfish are not the ‘simple creatures’ once thought: New study may change an understanding of our own brains

    Jellyfish are not the ‘simple creatures’ once thought: New study may change an understanding of our own brains

    Aspartame and autism: Drinking diet soda amid pregnancy linked to diagnosis in male offspring, says study

    Aspartame and autism: Drinking diet soda amid pregnancy linked to diagnosis in male offspring, says study

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InVivo Therapeutics Announces Topline Data from Pivotal INSPIRE 2.0 Study in Acute Spinal Cord Injury

admin by admin
March 17, 2023
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InVivo Therapeutics Announces Topline Data from Pivotal INSPIRE 2.0 Study in Acute Spinal Cord Injury

Research didn’t obtain major endpoint of outlined enchancment on customary impairment scale
InVivo to judge full knowledge set and strategic choices for the corporate

March 9, 2023

CAMBRIDGE, Mass.–(BUSINESS WIRE)–InVivo Therapeutics Holdings Corp. (Nasdaq: NVIV), a analysis and clinical-stage biomaterials and biotechnology firm with a deal with the therapy of spinal cord accidents (SCI), right this moment introduced topline outcomes from the corporate’s INSPIRE 2.0 examine, which was designed to judge the protection and possible advantage of InVivo’s investigational Neuro-Spinal Scaffold™, a bioresorbable scaffold-based system in growth for sufferers with acute SCI. The examine didn’t meet its major endpoint, which was assessed by the proportion of handled sufferers reaching an enchancment of a minimum of one American Spinal Damage Affiliation (ASIA) Impairment Scale (“AIS”) grade at six months post-scaffold implantation, versus a management group that acquired customary of care surgical procedure.

“We’re disenchanted by the result of this examine as therapies for spinal cord injury are so urgently wanted and we all know many within the SCI affected person and advocate neighborhood wait in hope for therapeutic choices. Now we have rigorously pursued the science and imagine that, upon full evaluation, the INSPIRE 2.0 knowledge set will present a major addition to the medical literature across the therapy of SCI,” mentioned Richard Toselli, M.D., InVivo’s President and Chief Govt Officer. “I lengthen our deepest due to our sufferers and medical websites who’ve supported InVivo’s work to deliver our science to sufferers, and the InVivo group who’ve tirelessly pursued our mission.”

InVivo administration will conduct a full evaluation of the examine knowledge set and plans to share its findings in full in a peer-reviewed medical venue at a later date. The corporate may also consider its strategic choices and supply an replace on company course when acceptable.

About InVivo Therapeutics

InVivo Therapeutics is a clinical-stage biomaterials and biotechnology firm with a deal with the therapy of spinal cord accidents. The corporate was based in 2005 with proprietary know-how co-invented by Robert Langer, Sc.D., and Joseph P. Vacanti, M.D. InVivo is headquartered in Cambridge, MA. For extra particulars, go to www.invivotherapeutics.com.

Secure Harbor Assertion

Any statements contained on this press launch that don’t describe historic details might represent forward-looking statements inside the which means of the federal securities legal guidelines. These statements could be recognized by phrases corresponding to “imagine,” “anticipate,” “intend,” “estimate,” “will,” “might,” “ought to,” “anticipate” and related expressions, and embody statements concerning the corporate’s evaluation of the total INSPIRE 2.0 knowledge set and analysis of strategic choices. Any forward-looking statements contained herein are primarily based on present expectations and are topic to a lot of dangers and uncertainties. Components that would trigger precise future outcomes to vary materially from present expectations embody, however are usually not restricted to, dangers and uncertainties regarding its means to establish strategic choices and different dangers recognized and described in additional element within the firm’s Annual Report on Type 10-Ok for the yr ended December 31, 2022, and in different filings that the corporate might make with the Securities and Trade Fee sooner or later. The corporate doesn’t undertake to replace these forward-looking statements.

Contacts

Buyers:
Bret Shapiro, Managing Associate
CORE IR
brets@coreir.com
(516) 222-2560

Media:
Tyler Reilly
Ten Bridge Communications
tyler@tenbridgecommunications.com
(617) 640-3595

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